Results of decitabine (5-aza-2'deoxycytidine) therapy in 130 patients with chronic myeloge
HM Kantarjian, S O'brien, J Cortes, FJ Giles, S Faderl, JP Issa, G Garcia-Manero, MB Rios, J Shan, M Andreeff, M Keating, M Talpaz
The estimated 3-year survival rate was less than 5% in the blastic phase and 27% in the accelerated phase.
摘自：http://www.epidna.com/showabstract.php?pmid=12879469
我更觉得Decitabine这种药物不可靠。
Friday, February 20, 2009
Decitabine的副作用
What side effects can this medication cause?
Decitabine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
* excessive tiredness
* pale skin
* headache
* dizziness
* confusion
* fast heartbeat
* difficulty falling asleep or staying asleep
* weakness
* shortness of breath
* nausea
* constipation
* diarrhea
* vomiting
* stomach pain
* heartburn or indigestion
* painful sores in mouth, or on tongue or lips
* red spots on the skin
* rash
* change in skin color
* hair loss
* joint or muscle pain
* chest discomfort or chest wall pain
* swelling of the hands, feet, ankles, lower legs, or stomach
* pain, swelling, or redness at injection spot
Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately:
* unusual bleeding or bruising
* hives
* itching
* difficulty breathing or swallowing
* swelling of the face
* sore throat, fever, chills, cough, or other signs of infection
Call your doctor immediately if you have any of the following symptoms of hyperglycemia (high blood sugar):
* extreme thirst
* frequent urination
* extreme hunger
* weakness
* blurred vision
Decitabine may cause other side effects. Call your doctor if you have any unusual problems while receiving this medication.
你真的愿意让患血癌的人冒这种风险去尝试吗？这种方法有康复的可能性吗？医生自己清不清楚给病人服用有多少成功康复的例子？还是书上这些就这么做呢？RM198,000的费用，如果不能康复，病人以后的生活如何呢？如果医生也糊里糊涂明知是无补于事都照做，是否可以相信他呢？
我认为，绝对不能盲目、毫无保留、失去理性地去相信医生，因为我看过许多认识接受医院医生治疗的癌症病患最终的下场就是十分痛苦地死去。我不禁怀疑，是因为上天把癌症设定成是不治之症，还是现代医学出现严重的漏洞。
你说我在挑战医学，我当然没有什么资格，但是我的确不能相信现在医学在这个癌症的层面能够扮演的角色。尤其是当事件发生在我周遭的亲人。
Decitabine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
* excessive tiredness
* pale skin
* headache
* dizziness
* confusion
* fast heartbeat
* difficulty falling asleep or staying asleep
* weakness
* shortness of breath
* nausea
* constipation
* diarrhea
* vomiting
* stomach pain
* heartburn or indigestion
* painful sores in mouth, or on tongue or lips
* red spots on the skin
* rash
* change in skin color
* hair loss
* joint or muscle pain
* chest discomfort or chest wall pain
* swelling of the hands, feet, ankles, lower legs, or stomach
* pain, swelling, or redness at injection spot
Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately:
* unusual bleeding or bruising
* hives
* itching
* difficulty breathing or swallowing
* swelling of the face
* sore throat, fever, chills, cough, or other signs of infection
Call your doctor immediately if you have any of the following symptoms of hyperglycemia (high blood sugar):
* extreme thirst
* frequent urination
* extreme hunger
* weakness
* blurred vision
Decitabine may cause other side effects. Call your doctor if you have any unusual problems while receiving this medication.
In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.
Symptoms of overdose may include:
- unusual bleeding or bruising
- sore throat, fever, chills, cough, or other signs of infection
你真的愿意让患血癌的人冒这种风险去尝试吗？这种方法有康复的可能性吗？医生自己清不清楚给病人服用有多少成功康复的例子？还是书上这些就这么做呢？RM198,000的费用，如果不能康复，病人以后的生活如何呢？如果医生也糊里糊涂明知是无补于事都照做，是否可以相信他呢？
我认为，绝对不能盲目、毫无保留、失去理性地去相信医生，因为我看过许多认识接受医院医生治疗的癌症病患最终的下场就是十分痛苦地死去。我不禁怀疑，是因为上天把癌症设定成是不治之症，还是现代医学出现严重的漏洞。
你说我在挑战医学，我当然没有什么资格，但是我的确不能相信现在医学在这个癌症的层面能够扮演的角色。尤其是当事件发生在我周遭的亲人。
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